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Fatigue and lethargy Clinical trials recorded fatigue as an occasional adverse event
It usually produces less weight loss than tirzepatide, but it has the longest outcomes record in the class: fewer cardiovascular events, slower kidney decline, and years of diabetes-trial safety data
10.5056/jnm.2010.16.4.407 56 LemboA.CamilleriM.McCallumR.SastreR.BretonC.SpenceS.et al (2016)
& Siegmund, B
Serious adverse events are rare in anecdotal reports, but anecdotal data cannot substitute for controlled trials
Efforts to standardize assays have improved this situation, but clinicians must still be aware of potential variability when interpreting results
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